Cargando…

Microhexagon gradient array directs spatial diversification of spinal motor neurons

Motor neuron diversification and regionalization are important hallmarks of spinal cord development and rely on fine spatiotemporal release of molecular cues. Here, we present a dedicated platform to engineer complex molecular profiles for directed neuronal differentiation. Methods: The technology,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lim, Geok Soon, Hor, Jin Hui, Ho, Nicholas R.Y., Wong, Chi Yan, Ng, Shi Yan, Soh, Boon Seng, Shao, Huilin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376181/ https://www.ncbi.nlm.nih.gov/pubmed/30809276 http://dx.doi.org/10.7150/thno.29755

Ejemplares similares

Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy
por: Hor, Jin Hui, et al.
Publicado: (2018)

Spinal cord organoids add an extra dimension to traditional motor neuron cultures
por: Winanto,, et al.
Publicado: (2019)

ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation
por: Hor, Jin-Hui, et al.
Publicado: (2020)

Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes
por: Fan, Yong, et al.
Publicado: (2018)

Griddient: a microfluidic array to generate reconfigurable gradients on-demand for spatial biology applications
por: Sanchez-de-Diego, Cristina, et al.
Publicado: (2023)

Organoid cultures of MELAS neural cells reveal hyperactive Notch signaling that impacts neurodevelopment
por: Winanto, et al.
Publicado: (2020)

Is the macrophyte diversification along the trophic gradient distinct enough for river monitoring?
por: Szoszkiewicz, Krzysztof, et al.
Publicado: (2016)

A dynamic continental moisture gradient drove Amazonian bird diversification
por: Silva, Sofia Marques, et al.
Publicado: (2019)

The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development
por: Wang, Wenxian, et al.
Publicado: (2022)

Gradient descent decomposition of force-field motor primitives optogenetically elicited for motor mapping of the murine lumbosacral spinal cord
por: Salmas, Paola, et al.
Publicado: (2023)

On-chip MIC by Combining Concentration Gradient Generator and Flanged Chamber Arrays
por: Zhang, Xiao-Yan, et al.
Publicado: (2020)

Gradient Annealing as a New Strategy to Fabricate Gradient Nanoparticle Array on Microwires
por: Chen, Anqi, et al.
Publicado: (2022)

Diversification of Bacterial Community Composition along a Temperature Gradient at a Thermal Spring
por: Everroad, R. Craig, et al.
Publicado: (2012)

Proofreading through spatial gradients
por: Galstyan, Vahe, et al.
Publicado: (2020)

Estimation of Spatial-Temporal Gait Parameters Using a Low-Cost Ultrasonic Motion Analysis System
por: Qi, Yongbin, et al.
Publicado: (2014)

Compost spatial heterogeneity promotes evolutionary diversification of a bacterium
por: van Houte, Stineke, et al.
Publicado: (2020)

Conical Gradient Junctions of Dendritic Viologen Arrays on Electrodes
por: Kawauchi, Takehiro, et al.
Publicado: (2015)

Control of the asymmetric growth of nanowire arrays with gradient profiles
por: Patiño Cárdenas, Juan, et al.
Publicado: (2021)

Cell spheroids culture array with modifiable chemical gradients
por: Yang, Panhui, et al.
Publicado: (2023)

Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells
por: Pek, Nicole Min Qian, et al.
Publicado: (2019)

Rapid Life-History Diversification of an Introduced Fish Species across a Localized Thermal Gradient
por: Zhu, Fengyue, et al.
Publicado: (2014)

Shared and unique patterns of phenotypic diversification along a stream gradient in two congeneric species
por: Jourdan, Jonas, et al.
Publicado: (2016)

The effects of mental fatigue on sport-specific motor performance among team sport athletes: A systematic scoping review
por: Yuan, Rui, et al.
Publicado: (2023)

Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
por: Chai, High Seng, et al.
Publicado: (2010)

A flexible electrode array for determining regions of motor function activated by epidural spinal cord stimulation in rats with spinal cord injury
por: Mao, Guang-Wei, et al.
Publicado: (2021)

Comparing spatial diversification and meta-population models in the Indo-Australian Archipelago
por: Chalmandrier, Loïc, et al.
Publicado: (2018)

Diversification across an altitudinal gradient in the Tiny Greenbul (Phyllastrephus debilis) from the Eastern Arc Mountains of Africa
por: Fuchs, Jérôme, et al.
Publicado: (2011)

Characterization of cocoa production, income diversification and shade tree management along a climate gradient in Ghana
por: Abdulai, Issaka, et al.
Publicado: (2018)

Functional Diversification of Motor Neuron-specific Isl1 Enhancers during Evolution
por: Kim, Namhee, et al.
Publicado: (2015)

Upregulation of the JAK-STAT pathway promotes maturation of human embryonic stem cell-derived cardiomyocytes
por: Ho, Beatrice Xuan, et al.
Publicado: (2021)

Spatial temperature gradients guide axonal outgrowth
por: Black, Bryan, et al.
Publicado: (2016)

Visual and modular detection of pathogen nucleic acids with enzyme–DNA molecular complexes
por: Ho, Nicholas R. Y., et al.
Publicado: (2018)

Population genetic structure of sharpbelly Hemiculter leucisculus (Basilesky, 1855) and morphological diversification along climate gradients in China
por: Wang, Lihong, et al.
Publicado: (2021)

Causes and consequences of pattern diversification in a spatially self-organizing microbial community
por: Goldschmidt, Felix, et al.
Publicado: (2021)

Crop diversification in the Egyptian Nile Region; viewpoint of spatial, climatic, and human features
por: Ammar, Esraa E.
Publicado: (2022)

Spatial normalization of array-CGH data
por: Neuvial, Pierre, et al.
Publicado: (2006)

DNA metabarcoding and spatial modelling link diet diversification with distribution homogeneity in European bats
por: Alberdi, Antton, et al.
Publicado: (2020)

Evolution of digestive enzymes and dietary diversification in birds
por: Chen, Yan-Hong, et al.
Publicado: (2019)

Physical constraints on the establishment of intracellular spatial gradients in bacteria
por: Tropini, Carolina, et al.
Publicado: (2012)

Spatial distribution of hand‐grasp motor task activity in spinal cord functional magnetic resonance imaging
por: Hemmerling, Kimberly J., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_frhtn4qekl249u5vud8ahgcj86