Cargando…
Evaluation of [(11)C]NMS-E973 as a PET tracer for in vivo visualisation of HSP90
Heat shock protein 90 is an ATP-dependent molecular chaperone important for folding, maturation and clearance of aberrantly expressed proteins and is abundantly expressed (1-2% of all proteins) in the cytosol of all normal cells. In some tumour cells, however, strong expression of HSP90 is also obse...
Autores principales: | Vermeulen, Koen, Naus, Evelyne, Ahamed, Muneer, Attili, Bala, Siemons, Maxime, Luyten, Kaat, Celen, Sofie, Schymkowitz, Joost, Rousseau, Frederic, Bormans, Guy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376183/ https://www.ncbi.nlm.nih.gov/pubmed/30809293 http://dx.doi.org/10.7150/thno.27213 |
Ejemplares similares
-
Hsp90 inhibitor NMS-E973 exerts the anticancer effect against glioblastoma via induction of PUMA-mediated apoptosis
por: Sun, Libo, et al.
Publicado: (2018) -
Synthetic Pept-Ins as a Generic Amyloid-Like Aggregation-Based
Platform for In Vivo PET Imaging of Intracellular
Targets
por: Siemons, Maxime, et al.
Publicado: (2021) -
Comparison of New Tau PET-Tracer Candidates With [(18)F]T808 and [(18)F]T807
por: Declercq, Lieven, et al.
Publicado: (2016) -
NMS pediatría
Publicado: (2009) -
NMS medicina interna /
Publicado: (2009)