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Bacterial killing by complement requires membrane attack complex formation via surface‐bound C5 convertases

The immune system kills bacteria by the formation of lytic membrane attack complexes (MACs), triggered when complement enzymes cleave C5. At present, it is not understood how the MAC perturbs the composite cell envelope of Gram‐negative bacteria. Here, we show that the role of C5 convertase enzymes...

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Detalles Bibliográficos
Autores principales:	Heesterbeek, Dani AC, Bardoel, Bart W, Parsons, Edward S, Bennett, Isabel, Ruyken, Maartje, Doorduijn, Dennis J, Gorham, Ronald D, Berends, Evelien TM, Pyne, Alice LB, Hoogenboom, Bart W, Rooijakkers, Suzan HM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376327/ https://www.ncbi.nlm.nih.gov/pubmed/30643019 http://dx.doi.org/10.15252/embj.201899852

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