Whole-Genome Sequencing of Two Extensively Drug-Resistant Mycobacterium tuberculosis Isolates from India

The emergence of extensively drug-resistant tuberculosis (XDR-TB) presents a considerable challenge and a public health concern due to the high mortality rate of this disease. Whole-genome sequencing (WGS) of XDR-TB isolates is thus essential for understanding the mechanism of drug resistance. Here...

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Detalles Bibliográficos
Autores principales: Rufai, Syed Beenish, Singh, Sarman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376416/
https://www.ncbi.nlm.nih.gov/pubmed/30801057
http://dx.doi.org/10.1128/MRA.00007-19
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author Rufai, Syed Beenish
Singh, Sarman
author_facet Rufai, Syed Beenish
Singh, Sarman
author_sort Rufai, Syed Beenish
collection PubMed
description The emergence of extensively drug-resistant tuberculosis (XDR-TB) presents a considerable challenge and a public health concern due to the high mortality rate of this disease. Whole-genome sequencing (WGS) of XDR-TB isolates is thus essential for understanding the mechanism of drug resistance. Here we report whole-genome sequences of two XDR-TB strains of two lineages from India.
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spelling pubmed-63764162019-02-22 Whole-Genome Sequencing of Two Extensively Drug-Resistant Mycobacterium tuberculosis Isolates from India Rufai, Syed Beenish Singh, Sarman Microbiol Resour Announc Genome Sequences The emergence of extensively drug-resistant tuberculosis (XDR-TB) presents a considerable challenge and a public health concern due to the high mortality rate of this disease. Whole-genome sequencing (WGS) of XDR-TB isolates is thus essential for understanding the mechanism of drug resistance. Here we report whole-genome sequences of two XDR-TB strains of two lineages from India. American Society for Microbiology 2019-02-14 /pmc/articles/PMC6376416/ /pubmed/30801057 http://dx.doi.org/10.1128/MRA.00007-19 Text en Copyright © 2019 Rufai and Singh. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Genome Sequences
Rufai, Syed Beenish
Singh, Sarman
Whole-Genome Sequencing of Two Extensively Drug-Resistant Mycobacterium tuberculosis Isolates from India
title Whole-Genome Sequencing of Two Extensively Drug-Resistant Mycobacterium tuberculosis Isolates from India
title_full Whole-Genome Sequencing of Two Extensively Drug-Resistant Mycobacterium tuberculosis Isolates from India
title_fullStr Whole-Genome Sequencing of Two Extensively Drug-Resistant Mycobacterium tuberculosis Isolates from India
title_full_unstemmed Whole-Genome Sequencing of Two Extensively Drug-Resistant Mycobacterium tuberculosis Isolates from India
title_short Whole-Genome Sequencing of Two Extensively Drug-Resistant Mycobacterium tuberculosis Isolates from India
title_sort whole-genome sequencing of two extensively drug-resistant mycobacterium tuberculosis isolates from india
topic Genome Sequences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376416/
https://www.ncbi.nlm.nih.gov/pubmed/30801057
http://dx.doi.org/10.1128/MRA.00007-19
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