VEGFC acts as a double-edged sword in renal cell carcinoma aggressiveness

Hypoxic zones are common features of metastatic tumors. Due to inactivation of the von Hippel-Lindau gene (VHL), renal cell carcinomas (RCC) show constitutive stabilization of the alpha subunit of the hypoxia-inducible factor (HIF). Thus, RCC represents a model of chronic hypoxia. Development of the...

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Detalles Bibliográficos
Autores principales: Ndiaye, Papa Diogop, Dufies, Maeva, Giuliano, Sandy, Douguet, Laetitia, Grépin, Renaud, Durivault, Jérôme, Lenormand, Philippe, Glisse, Natacha, Mintcheva, Janita, Vouret-Craviari, Valérie, Mograbi, Baharia, Wurmser, Maud, Ambrosetti, Damien, Rioux-Leclercq, Nathalie, Maire, Pascal, Pagès, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376471/
https://www.ncbi.nlm.nih.gov/pubmed/30809300
http://dx.doi.org/10.7150/thno.27794

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