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Enhanced Therapeutic Effect of RGD-Modified Polymeric Micelles Loaded With Low-Dose Methotrexate and Nimesulide on Rheumatoid Arthritis
Angiogenesis plays an essential role in the progression of rheumatoid arthritis (RA). RGD peptide shows high affinity and selectivity for integrin α(v)β(3,) which is one of the most extensively examined target of angiogenesis. Nimesulide could improve the anti-rheumatic profile of methotrexate. But...
Autores principales: | Wang, Yunlong, Liu, Zhongbing, Li, Ting, Chen, Lin, Lyu, Jiayao, Li, Chunhong, Lin, Yan, Hao, Na, Zhou, Meiling, Zhong, Zhirong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376478/ https://www.ncbi.nlm.nih.gov/pubmed/30809303 http://dx.doi.org/10.7150/thno.30418 |
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