Lectin-Mediated pH-Sensitive Doxorubicin Prodrug for Pre-Targeted Chemotherapy of Colorectal Cancer with Enhanced Efficacy and Reduced Side Effects

Doxorubicin (DOX) has been clinically used as a broad-spectrum chemotherapeutic agent for decades, but its clinical application is hindered by the lack of tumour specificity, severe cardiotoxicity and haematotoxicity. Pre-targeted strategies are highly tumour-specific, therapeutic approaches. Herein...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Meinan, Ma, Xiaotu, Zhang, Xin, Shi, Linqing, Liu, Tianyu, Liang, Xiaolong, Zhao, Huiyun, Li, Xiaoda, Li, Liqiang, Gao, Hannan, Jia, Bing, Wang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376480/
https://www.ncbi.nlm.nih.gov/pubmed/30809306
http://dx.doi.org/10.7150/thno.29989

Ejemplares similares

Ejemplares similares