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Synthesis and anti-human immunodeficiency virus activity of substituted (o,o-difluorophenyl)-linked-pyrimidines as potent non‐nucleoside reverse transcriptase inhibitors

With the worldwide number of human immunodeficiency virus positive patients stagnant and the increasing emergence of viral strains resistant to current treatment, the development of novel anti-human immunodeficiency virus drug candidates is a perpetual quest of medicinal chemists. Herein, we report...

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Detalles Bibliográficos
Autores principales: Čechová, Lucie, Dejmek, Milan, Baszczyňski, Ondřej, Šaman, David, Gao, Liping, Hu, Eric, Stepan, George, Jansa, Petr, Janeba, Zlatko, Šimon, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376552/
https://www.ncbi.nlm.nih.gov/pubmed/30788976
http://dx.doi.org/10.1177/2040206619826265

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