Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria

BACKGROUND: Rodent malaria models are extensively used to predict treatment outcomes in human infections. There is a constant need to improve and refine these models by innovating ways to apply new scientific findings and cutting edge technologies. In addition, and in accordance with the three R’s o...

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Detalles Bibliográficos
Autores principales: Caridha, Diana, Hickman, Mark, Xie, Lisa, Ngundam, Franklyn, Milner, Erin, Schenk, Amanda, Butler, Kirk, Nugent, Dylan, Lee, Patricia, Roncal, Norma, Leed, Susan, Hosford, Eve, Lee, Jangwoo, Sciotti, Richard J., Reichard, Gregory, Black, Chad, Kreishman-Deitrick, Mara, Li, Qigui, Vesely, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376706/
https://www.ncbi.nlm.nih.gov/pubmed/30767768
http://dx.doi.org/10.1186/s12936-019-2661-x

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