Variability and exposure–response relationships of isavuconazole plasma concentrations in the Phase 3 SECURE trial of patients with invasive mould diseases

OBJECTIVES: This analysis evaluated the variability of isavuconazole plasma concentrations between subjects and between sampling times, and assessed their relationship to outcomes for subjects with invasive fungal disease (IFD) in the SECURE trial. METHODS: Isavuconazole-treated subjects received 37...

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Detalles Bibliográficos
Autores principales: Kaindl, Thomas, Andes, David, Engelhardt, Marc, Saulay, Mikael, Larger, Patrice, Groll, Andreas H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376854/
https://www.ncbi.nlm.nih.gov/pubmed/30476108
http://dx.doi.org/10.1093/jac/dky463

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