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Anatomic and Cellular Niches for Mycobacterium tuberculosis in Latent Tuberculosis Infection

Latent tuberculosis has been recognized for over a century, but discovery of new niches, where Mycobacterium tuberculosis resides, continues. We evaluated literature on M.tuberculosis locations during latency, highlighting that mesenchymal and hematopoietic stem cells harbor organisms in sensitized...

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Detalles Bibliográficos
Autores principales: Mayito, Jonathan, Andia, Irene, Belay, Mulugeta, Jolliffe, David A, Kateete, David P, Reece, Stephen T, Martineau, Adrian R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376907/
https://www.ncbi.nlm.nih.gov/pubmed/30376080
http://dx.doi.org/10.1093/infdis/jiy579
Descripción
Sumario:Latent tuberculosis has been recognized for over a century, but discovery of new niches, where Mycobacterium tuberculosis resides, continues. We evaluated literature on M.tuberculosis locations during latency, highlighting that mesenchymal and hematopoietic stem cells harbor organisms in sensitized asymptomatic individuals.