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Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes
Neuronal activity-inducible gene transcription correlates with rapid and transient increases in histone acetylation at promoters and enhancers of activity-regulated genes. Exactly how histone acetylation modulates transcription of these genes has remained unknown. We used single-cell in situ transcr...
Autores principales: | Chen, Liang-Fu, Lin, Yen Ting, Gallegos, David A., Hazlett, Mariah F., Gómez-Schiavon, Mariana, Yang, Marty G., Kalmeta, Breanna, Zhou, Allen S., Holtzman, Liad, Gersbach, Charles A., Grandl, Jörg, Buchler, Nicolas E., West, Anne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376993/ https://www.ncbi.nlm.nih.gov/pubmed/30699347 http://dx.doi.org/10.1016/j.celrep.2019.01.032 |
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