Randomized clinical trials with run-in periods: frequency, characteristics and reporting

BACKGROUND: Run-in periods are occasionally used in randomized clinical trials to exclude patients after inclusion, but before randomization. In theory, run-in periods increase the probability of detecting a potential treatment effect, at the cost of possibly affecting external and internal validity...

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Detalles Bibliográficos
Autores principales: Laursen, David Ruben Teindl, Paludan-Müller, Asger Sand, Hróbjartsson, Asbjørn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377048/
https://www.ncbi.nlm.nih.gov/pubmed/30809104
http://dx.doi.org/10.2147/CLEP.S188752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377048/
https://www.ncbi.nlm.nih.gov/pubmed/30809104
http://dx.doi.org/10.2147/CLEP.S188752

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