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Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength

[Image: see text] Semiconductor nanowires can act as nanoscaled optical fibers, enabling them to guide and concentrate light emitted by surface-bound fluorophores, potentially enhancing the sensitivity of optical biosensing. While parameters such as the nanowire geometry and the fluorophore waveleng...

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Autores principales: Verardo, Damiano, Lindberg, Frida W., Anttu, Nicklas, Niman, Cassandra S., Lard, Mercy, Dabkowska, Aleksandra P., Nylander, Tommy, Månsson, Alf, Prinz, Christelle N., Linke, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377180/
https://www.ncbi.nlm.nih.gov/pubmed/30001138
http://dx.doi.org/10.1021/acs.nanolett.8b01360
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author Verardo, Damiano
Lindberg, Frida W.
Anttu, Nicklas
Niman, Cassandra S.
Lard, Mercy
Dabkowska, Aleksandra P.
Nylander, Tommy
Månsson, Alf
Prinz, Christelle N.
Linke, Heiner
author_facet Verardo, Damiano
Lindberg, Frida W.
Anttu, Nicklas
Niman, Cassandra S.
Lard, Mercy
Dabkowska, Aleksandra P.
Nylander, Tommy
Månsson, Alf
Prinz, Christelle N.
Linke, Heiner
author_sort Verardo, Damiano
collection PubMed
description [Image: see text] Semiconductor nanowires can act as nanoscaled optical fibers, enabling them to guide and concentrate light emitted by surface-bound fluorophores, potentially enhancing the sensitivity of optical biosensing. While parameters such as the nanowire geometry and the fluorophore wavelength can be expected to strongly influence this lightguiding effect, no detailed description of their effect on in-coupling of fluorescent emission is available to date. Here, we use confocal imaging to quantify the lightguiding effect in GaP nanowires as a function of nanowire geometry and light wavelength. Using a combination of finite-difference time-domain simulations and analytical approaches, we identify the role of multiple waveguide modes for the observed lightguiding. The normalized frequency parameter, based on the step-index approximation, predicts the lightguiding ability of the nanowires as a function of diameter and fluorophore wavelength, providing a useful guide for the design of optical biosensors based on nanowires.
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spelling pubmed-63771802019-02-19 Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength Verardo, Damiano Lindberg, Frida W. Anttu, Nicklas Niman, Cassandra S. Lard, Mercy Dabkowska, Aleksandra P. Nylander, Tommy Månsson, Alf Prinz, Christelle N. Linke, Heiner Nano Lett [Image: see text] Semiconductor nanowires can act as nanoscaled optical fibers, enabling them to guide and concentrate light emitted by surface-bound fluorophores, potentially enhancing the sensitivity of optical biosensing. While parameters such as the nanowire geometry and the fluorophore wavelength can be expected to strongly influence this lightguiding effect, no detailed description of their effect on in-coupling of fluorescent emission is available to date. Here, we use confocal imaging to quantify the lightguiding effect in GaP nanowires as a function of nanowire geometry and light wavelength. Using a combination of finite-difference time-domain simulations and analytical approaches, we identify the role of multiple waveguide modes for the observed lightguiding. The normalized frequency parameter, based on the step-index approximation, predicts the lightguiding ability of the nanowires as a function of diameter and fluorophore wavelength, providing a useful guide for the design of optical biosensors based on nanowires. American Chemical Society 2018-07-12 2018-08-08 /pmc/articles/PMC6377180/ /pubmed/30001138 http://dx.doi.org/10.1021/acs.nanolett.8b01360 Text en Copyright © 2018 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
spellingShingle Verardo, Damiano
Lindberg, Frida W.
Anttu, Nicklas
Niman, Cassandra S.
Lard, Mercy
Dabkowska, Aleksandra P.
Nylander, Tommy
Månsson, Alf
Prinz, Christelle N.
Linke, Heiner
Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength
title Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength
title_full Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength
title_fullStr Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength
title_full_unstemmed Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength
title_short Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength
title_sort nanowires for biosensing: lightguiding of fluorescence as a function of diameter and wavelength
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377180/
https://www.ncbi.nlm.nih.gov/pubmed/30001138
http://dx.doi.org/10.1021/acs.nanolett.8b01360
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