Cargando…

Loss of Solute Carrier Family 7 Member 2 Exacerbates Inflammation-Associated Colon Tumorigenesis

Solute carrier family 7 member 2 (SLC7A2, also known as CAT2) is an inducible transporter of the semi-essential amino acid L-arginine (L-Arg), which has been implicated in wound repair. We have reported that both SLC7A2 expression and L-Arg availability are decreased in colonic tissues from inflamma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coburn, Lori A., Singh, Kshipra, Asim, Mohammad, Barry, Daniel P., Allaman, Margaret M., Al-Greene, Nicole T., Hardbower, Dana M., Polosukhina, Dina, Williams, Christopher S., Delgado, Alberto G., Piazuelo, M. Blanca, Washington, M. Kay, Gobert, Alain P., Wilson, Keith T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377304/ https://www.ncbi.nlm.nih.gov/pubmed/30202097 http://dx.doi.org/10.1038/s41388-018-0492-9

Ejemplares similares

The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immunopathogenesis of Attaching and Effacing Bacteria
por: Singh, Kshipra, et al.
Publicado: (2016)

EGFR-mediated Macrophage Activation Promotes Colitis-associated Tumorigenesis
por: Hardbower, Dana M., et al.
Publicado: (2017)

Dietary Arginine Regulates Severity of Experimental Colitis and Affects the Colonic Microbiome
por: Singh, Kshipra, et al.
Publicado: (2019)

Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection
por: Gobert, Alain P., et al.
Publicado: (2018)

L-arginine Supplementation Improves Responses to Injury and Inflammation in Dextran Sulfate Sodium Colitis
por: Coburn, Lori A., et al.
Publicado: (2012)

Cationic Amino Acid Transporter 2 Enhances Innate Immunity during Helicobacter pylori Infection
por: Barry, Daniel P., et al.
Publicado: (2011)

The nutraceutical electrophile scavenger 2-hydroxybenzylamine (2-HOBA) attenuates gastric cancer development caused by Helicobacter pylori
por: Gobert, Alain P., et al.
Publicado: (2023)

High-Throughput Multi-Analyte Luminex Profiling Implicates Eotaxin-1 in Ulcerative Colitis
por: Coburn, Lori A., et al.
Publicado: (2013)

Loss of TFF1 promotes Helicobacter pylori-induced β-catenin activation and gastric tumorigenesis
por: Soutto, Mohammed, et al.
Publicado: (2015)

BVES Is Required for Maintenance of Colonic Epithelial Integrity in Experimental Colitis by Modifying Intestinal Permeability
por: Choksi, Yash A., et al.
Publicado: (2018)

Epithelial talin-1 protects mice from citrobacter rodentium-induced colitis by restricting bacterial crypt intrusion and enhancing t cell immunity
por: Latour, Yvonne L., et al.
Publicado: (2023)

Dietary Selenium Deficiency Exacerbates DSS-Induced Epithelial Injury and AOM/DSS-Induced Tumorigenesis
por: Barrett, Caitlyn W., et al.
Publicado: (2013)

Hypusination Orchestrates the Antimicrobial Response of Macrophages
por: Gobert, Alain P., et al.
Publicado: (2020)

Spermine Oxidase Mediates Helicobacter pylori-induced Gastric Inflammation, DNA Damage, and Carcinogenic Signaling
por: Sierra, Johanna C., et al.
Publicado: (2020)

MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors
por: Brown, Rachel E., et al.
Publicado: (2022)

Granzyme B prevents aberrant IL-17 production and intestinal pathogenicity in CD4(+) T cells
por: Hoek, Kristen L., et al.
Publicado: (2021)

Proteomic Approaches Identify Members of Cofilin Pathway Involved in Oral Tumorigenesis
por: Polachini, Giovana M., et al.
Publicado: (2012)

Evolutionary History of the Helicobacter pylori Genome: Implications for Gastric Carcinogenesis
por: Correa, Pelayo, et al.
Publicado: (2012)

Gastric cáncer: Overview
por: Piazuelo, M. Blanca, et al.
Publicado: (2013)

Lysyl oxidase family members in urological tumorigenesis and fibrosis
por: Li, Tao, et al.
Publicado: (2018)

The Role of DACT Family Members in Tumorigenesis and Tumor Progression
por: Zeng, Yu, et al.
Publicado: (2022)

Systems Modeling of the Role of Interleukin-21 in the Maintenance of Effector CD4(+) T Cell Responses during Chronic Helicobacter pylori Infection
por: Carbo, Adria, et al.
Publicado: (2014)

Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway
por: Gobert, Alain P., et al.
Publicado: (2019)

The Importance of Mitochondrial Pyruvate Carrier in Cancer Cell Metabolism and Tumorigenesis
por: Ruiz-Iglesias, Ainhoa, et al.
Publicado: (2021)

Vitamin D deficiency in the Apc(Pirc/+) rat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective
por: Irving, Amy A., et al.
Publicado: (2018)

The lipid peroxidation product EKODE exacerbates colonic inflammation and colon tumorigenesis
por: Lei, Lei, et al.
Publicado: (2021)

Iron deficiency linked to altered bile acid metabolism promotes Helicobacter pylori–induced inflammation–driven gastric carcinogenesis
por: Noto, Jennifer M., et al.
Publicado: (2022)

Activation of IGF1R by DARPP-32 promotes STAT3 signaling in gastric cancer cells
por: Zhu, Shoumin, et al.
Publicado: (2019)

Innate CD8αα(+) lymphocytes enhance anti‐CD40 antibody‐mediated colitis in mice
por: Kumar, Aaram A., et al.
Publicado: (2017)

Emerging Roles in the Biogenesis of Cytochrome c Oxidase for Members of the Mitochondrial Carrier Family
por: Ogunbona, Oluwaseun B., et al.
Publicado: (2019)

Serum Fatty Acids Are Correlated with Inflammatory Cytokines in Ulcerative Colitis
por: Wiese, Dawn M., et al.
Publicado: (2016)

Enterotoxigenic Bacteroides fragilis infection exacerbates tumorigenesis in AOM/DSS mouse model
por: Hwang, Soonjae, et al.
Publicado: (2020)

An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis
por: Chen, Yan-Jie, et al.
Publicado: (2022)

Pharmacologic Inhibition of β-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor
por: Polosukhina, Dina, et al.
Publicado: (2017)

Characterization of In Vivo Function(s) of Members of the Plant Mitochondrial Carrier Family
por: Nunes-Nesi, Adriano, et al.
Publicado: (2020)

The Western Dietary Pattern Combined with Vancomycin-Mediated Changes to the Gut Microbiome Exacerbates Colitis Severity and Colon Tumorigenesis
por: Aardema, Niklas D., et al.
Publicado: (2021)

Leucine Supplementation Exacerbates Morbidity in Male but Not Female Mice with Colorectal Cancer-Induced Cachexia
por: Schrems, Eleanor R., et al.
Publicado: (2023)

Memory for Semantically Related Objects Differentiates Cognitively Unimpaired Autosomal Dominant Mutation Carriers from Non-Carrier Family Members
por: Fox-Fuller, J. T., et al.
Publicado: (2023)

Modification of the Gastric Mucosal Microbiota by a Strain-Specific Helicobacter pylori Oncoprotein and Carcinogenic Histologic Phenotype
por: Noto, Jennifer M., et al.
Publicado: (2019)

Critical roles of PTPN family members regulated by non-coding RNAs in tumorigenesis and immunotherapy
por: Tang, Xiaolong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_377ko9oqf9io6g1vi5br3bfjsp