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Vascular smooth muscle-MAPK14 is required for neointimal hyperplasia by suppressing VSMC differentiation and inducing proliferation and inflammation

Injury-induced stenosis is a serious vascular complication. We previously reported that p38α (MAPK14), a redox-regulated p38MAPK family member was a negative regulator of the VSMC contractile phenotype in vitro. Here we evaluated the function of VSMC-MAPK14 in vivo in injury-induced neointima hyperp...

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Detalles Bibliográficos
Autores principales:	Wu, Wen, Zhang, Wei, Choi, Mihyun, Zhao, Jinjing, Gao, Ping, Xue, Min, Singer, Harold A., Jourd'heuil, David, Long, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377391/ https://www.ncbi.nlm.nih.gov/pubmed/30771750 http://dx.doi.org/10.1016/j.redox.2019.101137

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