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Evaluation of distant sequelae of breast cancer treatment among patients after breast-conserving surgery depending on the type of intervention in the axillary fossa

AIM OF THE STUDY: The goal of this work was to assess upper-limb sequelae among patients undergoing breast-conserving therapy (BCT) for breast cancer 5–6 years after the surgical procedure. MATERIAL AND METHODS: A controlled clinical study was conducted on 128 patients who had undergone surgery 5–6...

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Autores principales: Głowacka-Mrotek, Iwona, Tarkowska, Magdalena, Nowikiewicz, Tomasz, Siedlecki, Zygmunt, Zegarski, Wojciech, Hagner, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377421/
https://www.ncbi.nlm.nih.gov/pubmed/30783388
http://dx.doi.org/10.5114/wo.2018.82643
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author Głowacka-Mrotek, Iwona
Tarkowska, Magdalena
Nowikiewicz, Tomasz
Siedlecki, Zygmunt
Zegarski, Wojciech
Hagner, Wojciech
author_facet Głowacka-Mrotek, Iwona
Tarkowska, Magdalena
Nowikiewicz, Tomasz
Siedlecki, Zygmunt
Zegarski, Wojciech
Hagner, Wojciech
author_sort Głowacka-Mrotek, Iwona
collection PubMed
description AIM OF THE STUDY: The goal of this work was to assess upper-limb sequelae among patients undergoing breast-conserving therapy (BCT) for breast cancer 5–6 years after the surgical procedure. MATERIAL AND METHODS: A controlled clinical study was conducted on 128 patients who had undergone surgery 5–6 years prior. BCT + ALND (axillary lymph node dissection) was performed in 58 patients and 69 underwent BCT + SLND (sentinel lymph node dissection). Patients declared active participation in physiotherapy. The following parameters were assessed in studied subjects: range of motion in the shoulder joint, superficial sensation, upper limb circumference, skin sensation, and presence of winged scapula sign. RESULTS: Five to six years after BCT, patients who had undergone BCT + ALND presented with significantly poorer outcomes concerning upper limb range of motion on the operated side compared to the BCT + SLND group with regard to the following features: flexion (p = 0.00004), external rotation (p = 0.0292), and internal rotation (p = 0.0448). However, no statistically significant differences were noted between compared groups with regard to upper limb circumference and sensation disturbances. Statistically significant differences between limb on the operated side (operated limb – OL) vs. contralateral limb (healthy limb – HL) were noted in the BCT + SLND group with regard to the range of motion in extension (p = 0.0004), external rotation (p = 0.0055), and internal rotation (p < 0.0001), as well as the occurrence of winged scapula sign (p < 0.0001) and sensation disturbances (p < 0.0001). CONCLUSIONS: Our study demonstrated that both procedures are not free of distant sequelae, although the BCT + ALND group is more frequently affected.
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spelling pubmed-63774212019-02-19 Evaluation of distant sequelae of breast cancer treatment among patients after breast-conserving surgery depending on the type of intervention in the axillary fossa Głowacka-Mrotek, Iwona Tarkowska, Magdalena Nowikiewicz, Tomasz Siedlecki, Zygmunt Zegarski, Wojciech Hagner, Wojciech Contemp Oncol (Pozn) Original Paper AIM OF THE STUDY: The goal of this work was to assess upper-limb sequelae among patients undergoing breast-conserving therapy (BCT) for breast cancer 5–6 years after the surgical procedure. MATERIAL AND METHODS: A controlled clinical study was conducted on 128 patients who had undergone surgery 5–6 years prior. BCT + ALND (axillary lymph node dissection) was performed in 58 patients and 69 underwent BCT + SLND (sentinel lymph node dissection). Patients declared active participation in physiotherapy. The following parameters were assessed in studied subjects: range of motion in the shoulder joint, superficial sensation, upper limb circumference, skin sensation, and presence of winged scapula sign. RESULTS: Five to six years after BCT, patients who had undergone BCT + ALND presented with significantly poorer outcomes concerning upper limb range of motion on the operated side compared to the BCT + SLND group with regard to the following features: flexion (p = 0.00004), external rotation (p = 0.0292), and internal rotation (p = 0.0448). However, no statistically significant differences were noted between compared groups with regard to upper limb circumference and sensation disturbances. Statistically significant differences between limb on the operated side (operated limb – OL) vs. contralateral limb (healthy limb – HL) were noted in the BCT + SLND group with regard to the range of motion in extension (p = 0.0004), external rotation (p = 0.0055), and internal rotation (p < 0.0001), as well as the occurrence of winged scapula sign (p < 0.0001) and sensation disturbances (p < 0.0001). CONCLUSIONS: Our study demonstrated that both procedures are not free of distant sequelae, although the BCT + ALND group is more frequently affected. Termedia Publishing House 2018-12-31 2018 /pmc/articles/PMC6377421/ /pubmed/30783388 http://dx.doi.org/10.5114/wo.2018.82643 Text en Copyright: © 2018 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Głowacka-Mrotek, Iwona
Tarkowska, Magdalena
Nowikiewicz, Tomasz
Siedlecki, Zygmunt
Zegarski, Wojciech
Hagner, Wojciech
Evaluation of distant sequelae of breast cancer treatment among patients after breast-conserving surgery depending on the type of intervention in the axillary fossa
title Evaluation of distant sequelae of breast cancer treatment among patients after breast-conserving surgery depending on the type of intervention in the axillary fossa
title_full Evaluation of distant sequelae of breast cancer treatment among patients after breast-conserving surgery depending on the type of intervention in the axillary fossa
title_fullStr Evaluation of distant sequelae of breast cancer treatment among patients after breast-conserving surgery depending on the type of intervention in the axillary fossa
title_full_unstemmed Evaluation of distant sequelae of breast cancer treatment among patients after breast-conserving surgery depending on the type of intervention in the axillary fossa
title_short Evaluation of distant sequelae of breast cancer treatment among patients after breast-conserving surgery depending on the type of intervention in the axillary fossa
title_sort evaluation of distant sequelae of breast cancer treatment among patients after breast-conserving surgery depending on the type of intervention in the axillary fossa
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377421/
https://www.ncbi.nlm.nih.gov/pubmed/30783388
http://dx.doi.org/10.5114/wo.2018.82643
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