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Torsional stress generated by ADF/cofilin on cross-linked actin filaments boosts their severing
Proteins of the actin depolymerizing factor (ADF)/cofilin family are the central regulators of actin filament disassembly. A key function of ADF/cofilin is to sever actin filaments. However, how it does so in a physiological context, where filaments are interconnected and under mechanical stress, re...
Autores principales: | Wioland, Hugo, Jegou, Antoine, Romet-Lemonne, Guillaume |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377502/ https://www.ncbi.nlm.nih.gov/pubmed/30692249 http://dx.doi.org/10.1073/pnas.1812053116 |
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