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MiR-30a regulates cancer cell response to chemotherapy through SNAI1/IRS1/AKT pathway

Despite gemcitabine being the leading chemotherapeutic drug for pancreatic cancer, many patients still relapse due to the drug resistance. We previously reported the molecular link between FKBP51 mediated AKT inhibition and gemcitabine response in pancreatic cancers. However, the upstream regulator...

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Chen, Gang, Ma, Xuemei, Yang, Yao, Chen, Yali, Peng, Yihan, Bai, Zhigang, Zhang, Zhongtao, Pei, Huadong, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377638/
https://www.ncbi.nlm.nih.gov/pubmed/30770779
http://dx.doi.org/10.1038/s41419-019-1326-6