Autoantibody against β(1)-adrenoceptor promotes the differentiation of natural regulatory T cells from activated CD4(+) T cells by up-regulating AMPK-mediated fatty acid oxidation

Therapeutic adoptive transfer of natural regulatory T cells (nTreg, CD4(+) CD25(+) Foxp3(+) T cells) or in vivo selective expansion of nTreg cells has been demonstrated to improve the cardiac function in various cardiovascular disease models. The differentiation of nTreg cells is mediated by catecho...

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Detalles Bibliográficos
Autores principales: Xu, Wenli, Wu, Ye, Wang, Li, Bai, Yan, Du, Yunhui, Li, Yang, Cao, Ning, Zhao, Yuhui, Zhang, Youyi, Liu, Huirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377640/
https://www.ncbi.nlm.nih.gov/pubmed/30770790
http://dx.doi.org/10.1038/s41419-018-1209-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377640/
https://www.ncbi.nlm.nih.gov/pubmed/30770790
http://dx.doi.org/10.1038/s41419-018-1209-2

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