Cost-effective and robust genotyping using double-mismatch allele-specific quantitative PCR

For a wide range of diseases, SNPs in the genome are the underlying mechanism of dysfunction. Therefore, targeted detection of these variations is of high importance for early diagnosis and (familial) screenings. While allele-specific PCR has been around for many years, its adoption for SNP genotypi...

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Detalles Bibliográficos
Autores principales: Lefever, Steve, Rihani, Ali, Van der Meulen, Joni, Pattyn, Filip, Van Maerken, Tom, Van Dorpe, Jo, Hellemans, Jan, Vandesompele, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377641/
https://www.ncbi.nlm.nih.gov/pubmed/30770838
http://dx.doi.org/10.1038/s41598-019-38581-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377641/
https://www.ncbi.nlm.nih.gov/pubmed/30770838
http://dx.doi.org/10.1038/s41598-019-38581-z

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