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Brain region-specific alterations of RNA editing in PDE8A mRNA in suicide decedents

Phosphodiesterases (PDE) are key modulators of signal transduction and are involved in inflammatory cell activation, memory and cognition. There is a two-fold decrease in the expression of phosphodiesterase 8A (PDE8A) in the temporal cortex of major depressive disorder (MDD) patients. Here, we studi...

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Detalles Bibliográficos
Autores principales:	Chimienti, Fabrice, Cavarec, Laurent, Vincent, Laurent, Salvetat, Nicolas, Arango, Victoria, Underwood, Mark D., Mann, J. John, Pujol, Jean-François, Weissmann, Dinah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377659/ https://www.ncbi.nlm.nih.gov/pubmed/30770787 http://dx.doi.org/10.1038/s41398-018-0331-3

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