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Sirt3 suppresses calcium oxalate-induced renal tubular epithelial cell injury via modification of FoxO3a-mediated autophagy

High oxalic acid and calcium oxalate (CaOx)-induced renal tubular epithelial cell (TEC) injury plays a key role in nephrolithiasis. However, the mechanism remains unknown. Gene array analysis of the mice nephrolithiasis model indicated significant downregulation of sirtuin 3 (Sirt3) and activation o...

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Detalles Bibliográficos
Autores principales:	Peng, Yonghan, Yang, Cheng, Shi, Xiaolei, Li, Ling, Dong, Hao, Liu, Changcheng, Fang, Ziyu, Wang, Zeyu, Ming, Shaoxiong, Liu, Min, Xie, Bin, Gao, Xiaofeng, Sun, Yinghao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377683/ https://www.ncbi.nlm.nih.gov/pubmed/30674870 http://dx.doi.org/10.1038/s41419-018-1169-6

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