Cargando…
First-in-class positron emission tomography tracer for the glucagon receptor
ABSTRACT: The glucagon receptor (GCGR) is emerging as an important target in anti-diabetic therapy, especially as part of the pharmacology of dual glucagon-like peptide-1/glucagon (GLP-1/GCG) receptor agonists. However, currently, there are no suitable biomarkers that reliably demonstrate GCG recept...
Autores principales: | Velikyan, Irina, Haack, Torsten, Bossart, Martin, Evers, Andreas, Laitinen, Iina, Larsen, Philip, Plettenburg, Oliver, Johansson, Lars, Pierrou, Stefan, Wagner, Michael, Eriksson, Olof |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377692/ https://www.ncbi.nlm.nih.gov/pubmed/30771019 http://dx.doi.org/10.1186/s13550-019-0482-0 |
Ejemplares similares
-
Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates
por: Eriksson, Olof, et al.
Publicado: (2019) -
Automated GMP-Compliant Production of [(68)Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans
por: Wagner, Michael, et al.
Publicado: (2020) -
Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences
por: Velikyan, Irina, et al.
Publicado: (2022) -
Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes
por: Eriksson, Olof, et al.
Publicado: (2020) -
Glucagonlike Peptide-1 Receptor Imaging in Individuals with Type 2 Diabetes
por: Eriksson, Olof, et al.
Publicado: (2022)