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Insluin and epithelial growth factor (EGF) promote programmed death ligand 1(PD-L1) production and transport in colon cancer stem cells

BACKGROUND: Programmed cell death ligand 1 (PD-L1) is an important immune-inhibitory protein expressed on cancer cells to mediate cancer escape through interaction with PD-1 expressed on activated T lymphocytes (T cells). Previously, we reported that colon and breast cancer stem cells (CSCs) express...

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Detalles Bibliográficos
Autores principales: Chen, Mingshui, Sharma, Aditi, Lin, Yanling, Wu, Yanheng, He, Qi, Gu, Yushu, Xu, Zhi Ping, Monteiro, Michael, Gu, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377751/
https://www.ncbi.nlm.nih.gov/pubmed/30770752
http://dx.doi.org/10.1186/s12885-019-5364-3

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