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Macrophages derived exosomes deliver miR-223 to epithelial ovarian cancer cells to elicit a chemoresistant phenotype

BACKGROUND: How exosomal microRNAs (miRNAs) derived from macrophages contribute to the development of drug resistance in the context of the hypoxic tumor microenvironment in epithelial ovarian cancer (EOC) remains poorly understood. METHODS: The miRNA levels were detected by qRT-PCR. Protein levels...

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Detalles Bibliográficos
Autores principales:	Zhu, Xiaolan, Shen, Huiling, Yin, Xinming, Yang, Meiling, Wei, Hong, Chen, Qi, Feng, Fan, Liu, Yueqin, Xu, Wenlin, Li, Yuefeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377760/ https://www.ncbi.nlm.nih.gov/pubmed/30770776 http://dx.doi.org/10.1186/s13046-019-1095-1

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