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Evidence on Integrating Pharmacokinetics to Find Truly Therapeutic Agent for Alzheimer's Disease: Comparative Pharmacokinetics and Disposition Kinetics Profiles of Stereoisomers Isorhynchophylline and Rhynchophylline in Rats

Isorhynchophylline (IRN) and rhynchophylline (RN), a pair of stereoisomers, are tetracyclic oxindole alkaloids isolated from Uncaria rhynchophylla, a commonly used Chinese medicinal herb. These two compounds have drawn extensive attention due to their potent neuroprotective effects with promising th...

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Detalles Bibliográficos
Autores principales:	Zhang, Chunyuan, Wu, Xu, Xian, Yanfang, Zhu, Lin, Lin, Ge, Lin, Zhi-Xiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377964/ https://www.ncbi.nlm.nih.gov/pubmed/30854007 http://dx.doi.org/10.1155/2019/4016323

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