Cargando…

Cortical Visual Performance Test Setup for Parkinson's Disease Based on Motion Blur Orientation

Studies on Parkinson's disease (PD) are becoming very popular on multidisciplinary platforms. The development of predictable telemonitored early detection models has become closely related to many different research areas. The aim of this article is to develop a visual performance test that can...

Descripción completa

Detalles Bibliográficos
Autor principal: Isenkul, M. Erdem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377996/
https://www.ncbi.nlm.nih.gov/pubmed/30854187
http://dx.doi.org/10.1155/2019/3247608
_version_ 1783395841959002112
author Isenkul, M. Erdem
author_facet Isenkul, M. Erdem
author_sort Isenkul, M. Erdem
collection PubMed
description Studies on Parkinson's disease (PD) are becoming very popular on multidisciplinary platforms. The development of predictable telemonitored early detection models has become closely related to many different research areas. The aim of this article is to develop a visual performance test that can examine the effects of Parkinson's disease on the visual cortex, which can be a subtitle scoring test in UPDRS. However, instead of showing random images and asking for discrepancies between them, it is expected that the questions to be asked to patients should be provable in the existing cortex models, should be deduced between the images, and produce a reference threshold value to compare with the practical results. In a developed test, horizontal and vertical motion blur orientation was applied to natural image samples, and then neural outputs were produced by representing three (original-horizontal-vertical) image groups with the Layer 4 (L4) cortex model. This image representation is then compared with a filtering model which is very similar to thalamus' functionality. Thus, the linear problem-solving performance of the L4 cortex model is also addressed in the study. According to the obtained classification results, the L4 model produces high-performance success rates compared to the thalamic model, which shows the adaptation power of the visual cortex on the image pattern differences. In future studies, developed motion-based visual tests are planned to be applied to PD patient groups/controls, and their performances with mathematical threshold values will be examined.
format Online
Article
Text
id pubmed-6377996
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-63779962019-03-10 Cortical Visual Performance Test Setup for Parkinson's Disease Based on Motion Blur Orientation Isenkul, M. Erdem Parkinsons Dis Research Article Studies on Parkinson's disease (PD) are becoming very popular on multidisciplinary platforms. The development of predictable telemonitored early detection models has become closely related to many different research areas. The aim of this article is to develop a visual performance test that can examine the effects of Parkinson's disease on the visual cortex, which can be a subtitle scoring test in UPDRS. However, instead of showing random images and asking for discrepancies between them, it is expected that the questions to be asked to patients should be provable in the existing cortex models, should be deduced between the images, and produce a reference threshold value to compare with the practical results. In a developed test, horizontal and vertical motion blur orientation was applied to natural image samples, and then neural outputs were produced by representing three (original-horizontal-vertical) image groups with the Layer 4 (L4) cortex model. This image representation is then compared with a filtering model which is very similar to thalamus' functionality. Thus, the linear problem-solving performance of the L4 cortex model is also addressed in the study. According to the obtained classification results, the L4 model produces high-performance success rates compared to the thalamic model, which shows the adaptation power of the visual cortex on the image pattern differences. In future studies, developed motion-based visual tests are planned to be applied to PD patient groups/controls, and their performances with mathematical threshold values will be examined. Hindawi 2019-02-03 /pmc/articles/PMC6377996/ /pubmed/30854187 http://dx.doi.org/10.1155/2019/3247608 Text en Copyright © 2019 M. Erdem Isenkul. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Isenkul, M. Erdem
Cortical Visual Performance Test Setup for Parkinson's Disease Based on Motion Blur Orientation
title Cortical Visual Performance Test Setup for Parkinson's Disease Based on Motion Blur Orientation
title_full Cortical Visual Performance Test Setup for Parkinson's Disease Based on Motion Blur Orientation
title_fullStr Cortical Visual Performance Test Setup for Parkinson's Disease Based on Motion Blur Orientation
title_full_unstemmed Cortical Visual Performance Test Setup for Parkinson's Disease Based on Motion Blur Orientation
title_short Cortical Visual Performance Test Setup for Parkinson's Disease Based on Motion Blur Orientation
title_sort cortical visual performance test setup for parkinson's disease based on motion blur orientation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377996/
https://www.ncbi.nlm.nih.gov/pubmed/30854187
http://dx.doi.org/10.1155/2019/3247608
work_keys_str_mv AT isenkulmerdem corticalvisualperformancetestsetupforparkinsonsdiseasebasedonmotionblurorientation