Pioglitazone Ameliorates Atorvastatin-Induced Islet Cell Dysfunction through Activation of FFA1 in INS-1 Cells

Increasing evidence shows that statins increase the risk of new-onset diabetes mellitus, but the exact mechanism is not clearly known. Free fatty acid receptor 1 (FFA1) has been recognized to mediate insulin secretion, and pioglitazone has direct effects on glucose-stimulated insulin secretion in ad...

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Detalles Bibliográficos
Autores principales: Zhu, Kongbo, Qian, Linglin, Lin, Yanshan, An, Li, Mu, Guangjian, Ma, Genshan, Ren, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378042/
https://www.ncbi.nlm.nih.gov/pubmed/30863781
http://dx.doi.org/10.1155/2019/5245063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378042/
https://www.ncbi.nlm.nih.gov/pubmed/30863781
http://dx.doi.org/10.1155/2019/5245063

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