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Pioglitazone Ameliorates Atorvastatin-Induced Islet Cell Dysfunction through Activation of FFA1 in INS-1 Cells
Increasing evidence shows that statins increase the risk of new-onset diabetes mellitus, but the exact mechanism is not clearly known. Free fatty acid receptor 1 (FFA1) has been recognized to mediate insulin secretion, and pioglitazone has direct effects on glucose-stimulated insulin secretion in ad...
Autores principales: | Zhu, Kongbo, Qian, Linglin, Lin, Yanshan, An, Li, Mu, Guangjian, Ma, Genshan, Ren, Liqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378042/ https://www.ncbi.nlm.nih.gov/pubmed/30863781 http://dx.doi.org/10.1155/2019/5245063 |
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