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Mechanisms of Acupuncture Therapy for Simple Obesity: An Evidence-Based Review of Clinical and Animal Studies on Simple Obesity

Simple obesity is a worldwide epidemic associated with rapidly growing morbidity and mortality which imposes an enormous burden on individual and public health. As a part of Traditional Chinese Medicine (TCM), acupuncture has shown the positive efficacy in the management of simple obesity. In this a...

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Detalles Bibliográficos
Autores principales: Wang, Li-Hua, Huang, Wei, Wei, Dan, Ding, De-Guang, Liu, Yi-Ran, Wang, Jia-Jie, Zhou, Zhong-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378065/
https://www.ncbi.nlm.nih.gov/pubmed/30854010
http://dx.doi.org/10.1155/2019/5796381
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author Wang, Li-Hua
Huang, Wei
Wei, Dan
Ding, De-Guang
Liu, Yi-Ran
Wang, Jia-Jie
Zhou, Zhong-Yu
author_facet Wang, Li-Hua
Huang, Wei
Wei, Dan
Ding, De-Guang
Liu, Yi-Ran
Wang, Jia-Jie
Zhou, Zhong-Yu
author_sort Wang, Li-Hua
collection PubMed
description Simple obesity is a worldwide epidemic associated with rapidly growing morbidity and mortality which imposes an enormous burden on individual and public health. As a part of Traditional Chinese Medicine (TCM), acupuncture has shown the positive efficacy in the management of simple obesity. In this article, we comprehensively review the clinical and animal studies that demonstrated the potential mechanisms of acupuncture treatment for simple obesity. Clinical studies suggested that acupuncture regulates endocrine system, promotes digestion, attenuates oxidative stress, and modulates relevant molecules of metabolism in patients of simple obesity. Evidence from laboratory indicated that acupuncture regulates lipid metabolism, modulates inflammatory responses, and promotes white adipose tissue browning. Acupuncture also suppresses appetite through regulating appetite regulatory hormones and the downstream signaling pathway. The evidence from clinical and animal studies indicates that acupuncture induces multifaceted regulation through complex mechanisms and moreover a single factor may not be enough to explain the beneficial effects against simple obesity.
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spelling pubmed-63780652019-03-10 Mechanisms of Acupuncture Therapy for Simple Obesity: An Evidence-Based Review of Clinical and Animal Studies on Simple Obesity Wang, Li-Hua Huang, Wei Wei, Dan Ding, De-Guang Liu, Yi-Ran Wang, Jia-Jie Zhou, Zhong-Yu Evid Based Complement Alternat Med Review Article Simple obesity is a worldwide epidemic associated with rapidly growing morbidity and mortality which imposes an enormous burden on individual and public health. As a part of Traditional Chinese Medicine (TCM), acupuncture has shown the positive efficacy in the management of simple obesity. In this article, we comprehensively review the clinical and animal studies that demonstrated the potential mechanisms of acupuncture treatment for simple obesity. Clinical studies suggested that acupuncture regulates endocrine system, promotes digestion, attenuates oxidative stress, and modulates relevant molecules of metabolism in patients of simple obesity. Evidence from laboratory indicated that acupuncture regulates lipid metabolism, modulates inflammatory responses, and promotes white adipose tissue browning. Acupuncture also suppresses appetite through regulating appetite regulatory hormones and the downstream signaling pathway. The evidence from clinical and animal studies indicates that acupuncture induces multifaceted regulation through complex mechanisms and moreover a single factor may not be enough to explain the beneficial effects against simple obesity. Hindawi 2019-02-03 /pmc/articles/PMC6378065/ /pubmed/30854010 http://dx.doi.org/10.1155/2019/5796381 Text en Copyright © 2019 Li-Hua Wang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Wang, Li-Hua
Huang, Wei
Wei, Dan
Ding, De-Guang
Liu, Yi-Ran
Wang, Jia-Jie
Zhou, Zhong-Yu
Mechanisms of Acupuncture Therapy for Simple Obesity: An Evidence-Based Review of Clinical and Animal Studies on Simple Obesity
title Mechanisms of Acupuncture Therapy for Simple Obesity: An Evidence-Based Review of Clinical and Animal Studies on Simple Obesity
title_full Mechanisms of Acupuncture Therapy for Simple Obesity: An Evidence-Based Review of Clinical and Animal Studies on Simple Obesity
title_fullStr Mechanisms of Acupuncture Therapy for Simple Obesity: An Evidence-Based Review of Clinical and Animal Studies on Simple Obesity
title_full_unstemmed Mechanisms of Acupuncture Therapy for Simple Obesity: An Evidence-Based Review of Clinical and Animal Studies on Simple Obesity
title_short Mechanisms of Acupuncture Therapy for Simple Obesity: An Evidence-Based Review of Clinical and Animal Studies on Simple Obesity
title_sort mechanisms of acupuncture therapy for simple obesity: an evidence-based review of clinical and animal studies on simple obesity
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378065/
https://www.ncbi.nlm.nih.gov/pubmed/30854010
http://dx.doi.org/10.1155/2019/5796381
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