Cargando…

Highly efficient novel recombinant L-asparaginase with no glutaminase activity from a new halo-thermotolerant Bacillus strain

[Image: see text] Introduction: The bacterial enzyme has gained more attention in therapeutic application because of the higher substrate specificity and longer half-life. L-asparaginase is an important enzyme with known antineoplastic effect against acute lymphoblastic leukemia (ALL). Methods: Nove...

Descripción completa

Detalles Bibliográficos
Autores principales:	Safary, Azam, Moniri, Rezvan, Hamzeh-Mivehroud, Maryam, Dastmalchi, Siavoush
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tabriz University of Medical Sciences 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378094/ https://www.ncbi.nlm.nih.gov/pubmed/30788256 http://dx.doi.org/10.15171/bi.2019.03

Ejemplares similares

Expression and Biological Evaluation of an Engineered Recombinant L-asparaginase Designed by In Silico Method Based on Sequence of the Enzyme from Escherichia coli
por: Dastmalchi, Mahrokh, et al.
Publicado: (2023)

A Simple and Rapid Protocol for Producing Yeast Extract from Saccharomyces cerevisiae Suitable for Preparing Bacterial Culture Media
por: Zarei, Omid, et al.
Publicado: (2016)

Comparison of Different 2D and 3D-QSAR Methods on Activity Prediction of Histamine H3 Receptor Antagonists
por: Dastmalchi, Siavoush, et al.
Publicado: (2012)

In silico Evaluation of Crosslinking Effects on Denaturant m (eq) values and ΔCp upon Protein Unfolding
por: Hamzeh-Mivehroud, Maryam, et al.
Publicado: (2012)

An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors
por: Jafari, Behzad, et al.
Publicado: (2017)

Characterizing the Hot Spots Involved in RON-MSPβ Complex Formation Using In Silico Alanine Scanning Mutagenesis and Molecular Dynamics Simulation
por: Zarei, Omid, et al.
Publicado: (2017)

Identification of Novel Mutations in Arabidopsis thaliana DOF 4.2 Coding Gene
por: Jamshidi Kandjani, Omid, et al.
Publicado: (2021)

In-silico Investigation of Tubulin Binding Modes of a Series of Novel Antiproliferative Spiroisoxazoline Compounds Using Docking Studies
por: Abolhasani, Hoda, et al.
Publicado: (2015)

Characterization and applications of glutaminase free L-asparaginase from indigenous Bacillus halotolerans ASN9
por: Shafqat, Ifrah, et al.
Publicado: (2023)

Characterization of Novel Fragment Antibodies Against TNF-alpha Isolated Using Phage Display Technique
por: Alizadeha, Ali Akbar, et al.
Publicado: (2019)

Isolation and screening of l-asparaginase free of glutaminase and urease from fungal sp.
por: Doriya, Kruthi, et al.
Publicado: (2016)

The potential of halophilic and halotolerant bacteria for the production of antineoplastic enzymes: L-asparaginase and L-glutaminase
por: Shirazian, Pejman, et al.
Publicado: (2016)

Purification and Characterization of a Novel and Robust L-Asparaginase Having Low-Glutaminase Activity from Bacillus licheniformis: In Vitro Evaluation of Anti-Cancerous Properties
por: Mahajan, Richi V., et al.
Publicado: (2014)

Purification, characterization and immunogenicity assessment of glutaminase free L-asparaginase from Streptomyces brollosae NEAE-115
por: El-Naggar, Noura El-Ahmady, et al.
Publicado: (2018)

Optimization of glutaminase-free L-asparaginase production using mangrove endophytic Lysinibacillus fusiformis B27
por: Prihanto, Asep Awaludin, et al.
Publicado: (2020)

Filamentous Fungi Producing l-Asparaginase with Low Glutaminase Activity Isolated from Brazilian Savanna Soil
por: Freitas, Marcela, et al.
Publicado: (2021)

Expression, purification and DNA-binding properties of zinc finger domains of DOF proteins from Arabidopsis thaliana
por: Moghaddas Sani, Hakimeh, et al.
Publicado: (2018)

Microbes Producing L-Asparaginase free of Glutaminase and Urease isolated from Extreme Locations of Antarctic Soil and Moss
por: Ashok, Anup, et al.
Publicado: (2019)

In Silico Analysis of Glutaminase from Different Species of Escherichia and Bacillus
por: Irajie, Cambyz, et al.
Publicado: (2016)

6D-QSAR for predicting biological activity of human aldose reductase inhibitors using quasar receptor surface modeling
por: Sokouti, Babak, et al.
Publicado: (2023)

Novel halo- and thermo-tolerant Cohnella sp. A01 L-glutaminase: heterologous expression and biochemical characterization
por: Mosallatpour, Samaneh, et al.
Publicado: (2019)

A QSAR Study on the 4-Substituted Coumarins as Potent Tubulin Polymerization Inhibitors
por: Dinparast, Leila, et al.
Publicado: (2020)

L-Asparaginase from Penicillium sizovae Produced by a Recombinant Komagataella phaffii Strain
por: Freitas, Marcela, et al.
Publicado: (2022)

P320: A NOVEL MAMMALIAN L-ASPARAGINASE WITH NO L-GLUTAMINASE ACTIVITY IS HIGHLY EFFICACIOUS AGAINST T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA IN VIVO
por: Van Trimpont, Maaike, et al.
Publicado: (2023)

Streamlined Efficient Synthesis and Antioxidant Activity of γ-[Glutamyl]((n≥1))-tryptophan Peptides by Glutaminase from Bacillus amyloliquefaciens
por: He, Wenjiang, et al.
Publicado: (2023)

Novel Thermotolerant Amylase from Bacillus licheniformis Strain LB04: Purification, Characterization and Agar-Agarose
por: Silva-Salinas, Anaid, et al.
Publicado: (2021)

Efficient Open Fermentative Production of Polymer-Grade L-Lactate from Sugarcane Bagasse Hydrolysate by Thermotolerant Bacillus sp. Strain P38
por: Peng, Lili, et al.
Publicado: (2014)

Safety evaluation of the food enzyme asparaginase from the genetically modified Bacillus subtilis strain NZYM‐CK
por: Lambré, Claude, et al.
Publicado: (2023)

Application of Carbonic Nanosheets Based on Urea Precursors as Dispersive Solid Phase Extraction Adsorbent for Extraction of Methamphetamine from Urine Samples
por: Taghvimi, Arezou, et al.
Publicado: (2021)

Purification and Characterization of Glutaminase Free Asparaginase from Enterobacter cloacae: In-Vitro Evaluation of Cytotoxic Potential against Human Myeloid Leukemia HL-60 Cells
por: Husain, Islam, et al.
Publicado: (2016)

Recombinant l-glutaminase obtained from Geobacillus thermodenitrificans DSM-465: characterization and in silico elucidation of conserved structural domains
por: Shah, Luqman, et al.
Publicado: (2019)

Draft Genome Sequences of 18 Psychrotolerant and 2 Thermotolerant Strains Representative of Particular Ecotypes in the Bacillus cereus Group
por: Guinebretière, Marie-Hélène, et al.
Publicado: (2017)

Expression of Recombinant pET22b-LysK-Cysteine/Histidine-Dependent Amidohydrolase/Peptidase Bacteriophage Therapeutic Protein in Escherichia coli BL21 (DE3)
por: Kashani, Hamed Haddad, et al.
Publicado: (2015)

Fed-Batch Production of Saccharomyces cerevisiae L-Asparaginase II by Recombinant Pichia pastoris MUT(s) Strain
por: Rodrigues, David, et al.
Publicado: (2019)

Optimization of Culture Conditions for Production of the Anti-Leukemic Glutaminase Free L-Asparaginase by Newly Isolated Streptomyces olivaceus NEAE-119 Using Response Surface Methodology
por: El-Naggar, Noura El-Ahmady, et al.
Publicado: (2015)

Alignment independent 3D-QSAR studies and molecular dynamics simulations for the identification of potent and selective S1P(1) receptor agonists
por: Alizadeh, Ali Akbar, et al.
Publicado: (2020)

Preparation and Antiproliferative Activity Evaluation of Juglone-Loaded BSA Nanoparticles
por: Jahanban-Esfahlan, Ali, et al.
Publicado: (2022)

Drug Repurposing for Identification of S1P1 Agonists with Potential Application in Multiple Sclerosis Using In Silico Drug Design Approaches
por: Alizadeh, Ali Akbar, et al.
Publicado: (2023)

Expression of a recombinant bacterial l-asparaginase in human cells
por: Dantas, Raquel Caminha, et al.
Publicado: (2019)

Complete Genome Sequence of a thermotolerant sporogenic lactic acid bacterium, Bacillus coagulans strain 36D1
por: Rhee, Mun Su, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_5so1o0urgs0r9vnb62fbtk13hh