Dendritic remodeling of D1 neurons by RhoA/Rho-kinase mediates depression-like behavior

Depression alters the structure and function of brain reward circuitry. Preclinical evidence suggests that medium spiny neurons (MSNs) in the nucleus accumbens (NAc) undergo structural plasticity, however the molecular mechanism and behavioral significance is poorly understood. Here we report that a...

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Detalles Bibliográficos
Autores principales: Fox, Megan E., Chandra, Ramesh, Menken, Miriam S., Larkin, Emily J, Nam, Hyungwoo, Engeln, Michel, Francis, T. Chase, Lobo, Mary Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378138/
https://www.ncbi.nlm.nih.gov/pubmed/30120419
http://dx.doi.org/10.1038/s41380-018-0211-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378138/
https://www.ncbi.nlm.nih.gov/pubmed/30120419
http://dx.doi.org/10.1038/s41380-018-0211-5

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