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Dendritic remodeling of D1 neurons by RhoA/Rho-kinase mediates depression-like behavior
Depression alters the structure and function of brain reward circuitry. Preclinical evidence suggests that medium spiny neurons (MSNs) in the nucleus accumbens (NAc) undergo structural plasticity, however the molecular mechanism and behavioral significance is poorly understood. Here we report that a...
Autores principales: | Fox, Megan E., Chandra, Ramesh, Menken, Miriam S., Larkin, Emily J, Nam, Hyungwoo, Engeln, Michel, Francis, T. Chase, Lobo, Mary Kay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378138/ https://www.ncbi.nlm.nih.gov/pubmed/30120419 http://dx.doi.org/10.1038/s41380-018-0211-5 |
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