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Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling

In addition to the known antitumour effects of ursolic acid (UA), increasing evidence indicates that this molecule plays a role in cardiac protection. In this study, the effects of ursolic acid on the heart in mice treated with doxorubicin (DOX) were assessed. The results showed that ursolic acid im...

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Detalles Bibliográficos
Autores principales: Mu, Haiman, Liu, Haiwen, Zhang, Jiayi, Huang, Jianhua, Zhu, Chen, Lu, Yue, Shi, Yueping, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378202/
https://www.ncbi.nlm.nih.gov/pubmed/30609217
http://dx.doi.org/10.1111/jcmm.14130