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Chemically modified liposomes carrying TRAIL target activated hepatic stellate cells and ameliorate hepatic fibrosis in vitro and in vivo

At present, no satisfactory anti‐liver fibrosis drugs have been used clinically due to the poor targeting ability and short half‐life period. This study aimed to explore the effects of a new TRAIL (TNF‐related apoptosis‐inducing ligand) preparation that can target aHSCs (activated hepatic stellate c...

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Detalles Bibliográficos
Autores principales: Li, Qinghua, Ding, Youcheng, Guo, Xinlai, Luo, Shenggen, Zhuang, Huiren, Zhou, JingE, Xu, Nan, Yan, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378220/
https://www.ncbi.nlm.nih.gov/pubmed/30592139
http://dx.doi.org/10.1111/jcmm.14097