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WW Domain-Containing Proteins YAP and TAZ in the Hippo Pathway as Key Regulators in Stemness Maintenance, Tissue Homeostasis, and Tumorigenesis

The Hippo pathway is a conserved signaling pathway originally defined in Drosophila melanogaster two decades ago. Deregulation of the Hippo pathway leads to significant overgrowth in phenotypes and ultimately initiation of tumorigenesis in various tissues. The major WW domain proteins in the Hippo p...

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Detalles Bibliográficos
Autores principales:	Chen, Yu-An, Lu, Chen-Yu, Cheng, Tian-You, Pan, Szu-Hua, Chen, Hsin-Fu, Chang, Nan-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378284/ https://www.ncbi.nlm.nih.gov/pubmed/30805310 http://dx.doi.org/10.3389/fonc.2019.00060

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