Constitutive overexpression of TNF in BPSM1 mice causes iBALT and bone marrow nodular lymphocytic hyperplasia

BPSM1 (Bone phenotype spontaneous mutant 1) mice develop severe polyarthritis and heart valve disease as a result of a spontaneous mutation in the Tnf gene. In these mice, the insertion of a retrotransposon in the 3' untranslated region of Tnf causes a large increase in the expression of the cy...

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Detalles Bibliográficos
Autores principales: Seillet, Cyril, Arvell, Elyas H, Lacey, Derek, Stutz, Michael D, Pellegrini, Marc, Whitehead, Lachlan, Rimes, Joel, Hawkins, Edwin D, Roediger, Ben, Belz, Gabrielle T, Bouillet, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378607/
https://www.ncbi.nlm.nih.gov/pubmed/30107066
http://dx.doi.org/10.1111/imcb.12197

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