Cargando…

IL‐33 regulates cytokine production and neutrophil recruitment via the p38 MAPK‐activated kinases MK2/3

IL‐33 is an IL‐1‐related cytokine that can act as an alarmin when released from necrotic cells. Once released, it can target various immune cells including mast cells, innate lymphoid cells and T cells to elicit a Th2‐like immune response. We show here that bone marrow‐derived mast cells produce IL‐...

Descripción completa

Detalles Bibliográficos
Autores principales:	McCarthy, Pierre C, Phair, Iain R, Greger, Corinna, Pardali, Katerina, McGuire, Victoria A, Clark, Andrew R, Gaestel, Matthias, Arthur, J Simon C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378613/ https://www.ncbi.nlm.nih.gov/pubmed/30171775 http://dx.doi.org/10.1111/imcb.12200

Ejemplares similares

p38 MAPK signalling regulates cytokine production in IL-33 stimulated Type 2 Innate Lymphoid cells
por: Petrova, Tsvetana, et al.
Publicado: (2020)

p38(MAPK)/MK2 signaling stimulates host cells autophagy pathways to restrict Salmonella infection
por: Suwandi, Abdulhadi, et al.
Publicado: (2023)

Stress-dependent phosphorylation of myocardin-related transcription factor A (MRTF-A) by the p38(MAPK)/MK2 axis
por: Ronkina, Natalia, et al.
Publicado: (2016)

p38(MAPK)/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex
por: Tiedje, Christopher, et al.
Publicado: (2015)

The p38/MK2 Axis in Monocytes of Fibromyalgia Syndrome Patients: An Explorative Study
por: Nugraha, Boya, et al.
Publicado: (2021)

Phosphorylation of steroid receptor coactivator-3 (SRC-3) at serine 857 is regulated by the p38(MAPK)-MK2 axis and affects NF-κB-mediated transcription
por: Shrestha, Anup, et al.
Publicado: (2020)

Sexual Dimorphism in MAPK-Activated Protein Kinase-2 (MK2) Regulation of RANKL-Induced Osteoclastogenesis in Osteoclast Progenitor Subpopulations
por: Herbert, Bethany A., et al.
Publicado: (2015)

Regulation of monocyte subset proinflammatory responses within the lung microvasculature by the p38 MAPK/MK2 pathway
por: O'Dea, Kieran P., et al.
Publicado: (2011)

Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38(MAPK)-induced heat shock protein 27 phosphorylation
por: Shiryaev, Alexey, et al.
Publicado: (2011)

The p38/MK2-Driven Exchange between Tristetraprolin and HuR Regulates AU–Rich Element–Dependent Translation
por: Tiedje, Christopher, et al.
Publicado: (2012)

Revisiting p38 Mitogen-Activated Protein Kinases (MAPK) in Inflammatory Arthritis: A Narrative of the Emergence of MAPK-Activated Protein Kinase Inhibitors (MK2i)
por: Ganguly, Payal, et al.
Publicado: (2023)

Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathway
por: Maruyama, Junichi, et al.
Publicado: (2016)

The p38(MAPK)-MK2 Signaling Axis as a Critical Link Between Inflammation and Synaptic Transmission
por: Beamer, Edward, et al.
Publicado: (2021)

Cooperative and distinct functions of MK2 and MK3 in the regulation of the macrophage transcriptional response to lipopolysaccharide
por: Ehlting, Christian, et al.
Publicado: (2019)

Selective inhibition of the p38α MAPK–MK2 axis inhibits inflammatory cues including inflammasome priming signals
por: Wang, Chun, et al.
Publicado: (2018)

MK2 and Fas Receptor Contribute to the Severity of CNS Demyelination
por: Tietz, Silvia M., et al.
Publicado: (2014)

A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury
por: Ashraf, Muhammad Imtiaz, et al.
Publicado: (2014)

Fisetin alleviates sepsis-induced multiple organ dysfunction in mice via inhibiting p38 MAPK/MK2 signaling
por: Zhang, Hai-feng, et al.
Publicado: (2020)

Crucial Roles of the Protein Kinases MK2 and MK3 in a Mouse Model of Glomerulonephritis
por: Guess, Adam J., et al.
Publicado: (2013)

Induction of oxidative metabolism by the p38α/MK2 pathway
por: Trempolec, Natalia, et al.
Publicado: (2017)

Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhibition and Phosphoproteomics in HepaRG Cells
por: Lynch, Katherine D., et al.
Publicado: (2023)

T cell LFA-1-induced proinflammatory mRNA stabilization is mediated by the p38 pathway kinase MK2 in a process regulated by hnRNPs C, H1 and K
por: Rao, Gautham K., et al.
Publicado: (2018)

The Conserved CNOT1 Interaction Motif of Tristetraprolin Regulates ARE-mRNA Decay Independently of the p38 MAPK-MK2 Kinase Pathway
por: Carreño, Alberto, et al.
Publicado: (2022)

The p38 MAPK Regulates IL-24 Expression by Stabilization of the 3′ UTR of IL-24 mRNA
por: Otkjaer, Kristian, et al.
Publicado: (2010)

The MK2/3 cascade regulates AMPAR trafficking and cognitive flexibility
por: Eales, Katherine L., et al.
Publicado: (2014)

The IL-33-induced p38-/JNK1/2-TNFα axis is antagonized by activation of β-adrenergic-receptors in dendritic cells
por: Helbig, Christiane, et al.
Publicado: (2020)

MAPK-Activated Protein Kinases (MKs): Novel Insights and Challenges
por: Gaestel, Matthias
Publicado: (2016)

MAPKAP kinase 2 (MK2)-dependent and independent models of blister formation in pemphigus vulgaris
por: Mao, Xuming, et al.
Publicado: (2013)

Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression
por: Boucas, Jorge, et al.
Publicado: (2015)

MiR-33 promotes myocardial fibrosis by inhibiting MMP16 and stimulating p38 MAPK signaling
por: Chen, Zhen, et al.
Publicado: (2018)

p38 MAPK-MK2 pathway regulates the heat-stress-induced accumulation of reactive oxygen species that mediates apoptotic cell death in glial cells
por: Li, Hongbo, et al.
Publicado: (2018)

Alleviation of Microglial Activation Induced by p38 MAPK/MK2/PGE(2) Axis by Capsaicin: Potential Involvement of other than TRPV1 Mechanism/s
por: Bhatia, Harsharan S., et al.
Publicado: (2017)

p38-MAPK Signals Survival by Phosphorylation of Caspase-8 and Caspase-3 in Human Neutrophils
por: Alvarado-Kristensson, Maria, et al.
Publicado: (2004)

p38 MAPK in MDS
por: Gañán‐Gómez, Irene, et al.
Publicado: (2015)

IL-33 induces granzyme C expression in murine mast cells via an MSK1/2-CREB-dependent pathway
por: Phair, Iain R., et al.
Publicado: (2022)

The transcriptional regulation and cell-specific expression of the MAPK-activated protein kinase MK5
por: Gerits, Nancy, et al.
Publicado: (2009)

Neutrophil elastase suppression by medium-molecular-weight hydroxyethylstarch in orthopaedic surgery
por: Walker, R, et al.
Publicado: (2007)

p38 MAPK in cardioprotection – are we there yet?
por: Martin, E D, et al.
Publicado: (2015)

Normal endothelial but impaired arterial development in MAP-Kinase activated protein kinase 2 (MK2) deficient mice
por: Napp, L. Christian, et al.
Publicado: (2016)

MK2 Is Required for Neutrophil-Derived ROS Production and Inflammatory Bowel Disease
por: Zhang, Tao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tj237nkt88fsfr5qb0hda8ab6r