Coupling of PARP1-mediated chromatin structural changes to transcriptional RNA polymerase II elongation and cotranscriptional splicing

BACKGROUND: Recently, we showed that PARP1 is involved in cotranscriptional splicing, possibly by bridging chromatin to RNA and recruiting splicing factors. It also can influence alternative splicing decisions through the regulation of RNAPII elongation. In this study, we investigated the effect of...

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Detalles Bibliográficos
Autores principales: Matveeva, Elena A., Al-Tinawi, Qamar M. H., Rouchka, Eric C., Fondufe-Mittendorf, Yvonne N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378753/
https://www.ncbi.nlm.nih.gov/pubmed/30777121
http://dx.doi.org/10.1186/s13072-019-0261-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378753/
https://www.ncbi.nlm.nih.gov/pubmed/30777121
http://dx.doi.org/10.1186/s13072-019-0261-1

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