SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis

When properly employed, targeted therapies are effective cancer treatments. However, the development of such therapies requires the identification of targetable drivers of cancer development and metastasis. The expression and nuclear localization of the transcriptional coactivators Yes-associated pr...

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Detalles Bibliográficos
Autores principales: Lamar, John M., Xiao, Yuxuan, Norton, Emily, Jiang, Zhi-Gang, Gerhard, Genevieve M., Kooner, Simrin, Warren, Janine S. A., Hynes, Richard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378979/
https://www.ncbi.nlm.nih.gov/pubmed/30559289
http://dx.doi.org/10.1074/jbc.RA118.004364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378979/
https://www.ncbi.nlm.nih.gov/pubmed/30559289
http://dx.doi.org/10.1074/jbc.RA118.004364

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