3′ Branch ligation: a novel method to ligate non-complementary DNA to recessed or internal 3′OH ends in DNA or RNA

Nucleic acid ligases are crucial enzymes that repair breaks in DNA or RNA during synthesis, repair and recombination. Various genomic tools have been developed using the diverse activities of DNA/RNA ligases. Herein, we demonstrate a non-conventional ability of T4 DNA ligase to insert 5′ phosphoryla...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Xi, Yang, Zhang, Wenwei, Wang, Weimao, Shen, Hanjie, Wang, Xiaojue, Zhao, Xia, Alexeev, Andrei, Peters, Brock A, Albert, Alayna, Xu, Xu, Ren, Han, Wang, Ou, Kirkconnell, Killeen, Perazich, Helena, Clark, Sonya, Hurowitz, Evan, Chen, Ao, Xu, Xun, Drmanac, Radoje, Jiang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379041/
https://www.ncbi.nlm.nih.gov/pubmed/30428014
http://dx.doi.org/10.1093/dnares/dsy037

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