Cargando…

Mi-2/NuRD complex protects stem cell progeny from mitogenic Notch signaling

To progress towards differentiation, progeny of stem cells need to extinguish expression of stem-cell maintenance genes. Failures in such mechanisms can drive tumorigenesis. In Drosophila neural stem cell (NSC) lineages, excessive Notch signalling results in supernumerary NSCs causing hyperplasia. H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zacharioudaki, Evanthia, Falo Sanjuan, Julia, Bray, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379090/ https://www.ncbi.nlm.nih.gov/pubmed/30694174 http://dx.doi.org/10.7554/eLife.41637

Ejemplares similares

NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins
por: Campbell, Amy E, et al.
Publicado: (2018)

Insight into the Architecture of the NuRD Complex: STRUCTURE OF THE RbAp48-MTA1 SUBCOMPLEX
por: Alqarni, Saad S. M., et al.
Publicado: (2014)

Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms
por: Scacchetti, Alessandro, et al.
Publicado: (2020)

Transitions in cell potency during early mouse development are driven by Notch
por: Menchero, Sergio, et al.
Publicado: (2019)

Localization of Drosophila CENP-A to non-centromeric sites depends on the NuRD complex
por: Demirdizen, Engin, et al.
Publicado: (2019)

Insights into Association of the NuRD Complex with FOG-1 from the Crystal Structure of an RbAp48·FOG-1 Complex
por: Lejon, Sara, et al.
Publicado: (2011)

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality
por: Hoffmeister, Helen, et al.
Publicado: (2017)

ZEB1 Is Regulated by K811 Acetylation to Promote Stability, NuRD Complex Interactions, EMT, and NSCLC Metastasis
por: Perez-Oquendo, Mabel, et al.
Publicado: (2023)

Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development
por: Zhou, Li, et al.
Publicado: (2018)

NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells
por: Kloet, Susan L., et al.
Publicado: (2018)

Viral miRNA adaptor differentially recruits miRNAs to target mRNAs through alternative base-pairing
por: Gorbea, Carlos, et al.
Publicado: (2019)

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex
por: Ivanochko, Danton, et al.
Publicado: (2019)

Rapid DNA replication origin licensing protects stem cell pluripotency
por: Matson, Jacob Peter, et al.
Publicado: (2017)

Correction: Rapid DNA replication origin licensing protects stem cell pluripotency
por: Matson, Jacob Peter, et al.
Publicado: (2019)

miR-125-chinmo pathway regulates dietary restriction-dependent enhancement of lifespan in Drosophila
por: Pandey, Manish, et al.
Publicado: (2021)

The tardigrade damage suppressor protein binds to nucleosomes and protects DNA from hydroxyl radicals
por: Chavez, Carolina, et al.
Publicado: (2019)

The histone deacetylase complex MiDAC regulates a neurodevelopmental gene expression program to control neurite outgrowth
por: Mondal, Baisakhi, et al.
Publicado: (2020)

Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in Saccharomyces cerevisiae
por: Rosas Bringas, Fernando Rodrigo, et al.
Publicado: (2022)

An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning
por: Ehrmann, Ingrid, et al.
Publicado: (2019)

Zeb2 Recruits HDAC-NuRD to Inhibit Notch and Controls Schwann Cell Differentiation and Remyelination
por: Wu, Lai Man Natalie, et al.
Publicado: (2016)

STAT3 promotes RNA polymerase III-directed transcription by controlling the miR-106a-5p/TP73 axis
por: Zhang, Cheng, et al.
Publicado: (2023)

Repressive H3K9me2 protects lifespan against the transgenerational burden of COMPASS activity in C. elegans
por: Lee, Teresa Wei-sy, et al.
Publicado: (2019)

Identification of protein-protected mRNA fragments and structured excised intron RNAs in human plasma by TGIRT-seq peak calling
por: Yao, Jun, et al.
Publicado: (2020)

Specific NuRD components are required for fin regeneration in zebrafish
por: Pfefferli, Catherine, et al.
Publicado: (2014)

Chromatin Remodeling Complex NuRD in Neurodevelopment and Neurodevelopmental Disorders
por: Hoffmann, Anke, et al.
Publicado: (2019)

The topology of chromatin-binding domains in the NuRD deacetylase complex
por: Millard, Christopher J, et al.
Publicado: (2020)

The NuRD complex cooperates with SALL4 to orchestrate reprogramming
por: Wang, Bo, et al.
Publicado: (2023)

Disruption of the MBD2-NuRD complex but not MBD3-NuRD induces high level HbF expression in human adult erythroid cells
por: Yu, Xiaofei, et al.
Publicado: (2019)

Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer)
por: Zhang, Yue
Publicado: (2011)

Reporter-ChIP-nexus reveals strong contribution of the Drosophila initiator sequence to RNA polymerase pausing
por: Shao, Wanqing, et al.
Publicado: (2019)

Distinct ‘safe zones’ at the nuclear envelope ensure robust replication of heterochromatic chromosome regions
por: Ebrahimi, Hani, et al.
Publicado: (2018)

The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription
por: Hildreth, A Elizabeth, et al.
Publicado: (2020)

A simple mechanism for integration of quorum sensing and cAMP signalling in Vibrio cholerae
por: Walker, Lucas M, et al.
Publicado: (2023)

PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading
por: Rona, Gergely, et al.
Publicado: (2018)

Characterization of the nuclear import of the human CHD4–NuRD complex
por: Hoffmeister, Helen, et al.
Publicado: (2023)

The NuRD Complex in Neurodevelopment and Disease: A Case of Sliding Doors
por: Boulasiki, Paraskevi, et al.
Publicado: (2023)

Mutants in the Mouse NuRD/Mi2 Component P66α Are Embryonic Lethal
por: Marino, Susan, et al.
Publicado: (2007)

The TRIM-NHL protein NHL-2 is a co-factor in the nuclear and somatic RNAi pathways in C. elegans
por: Davis, Gregory M, et al.
Publicado: (2018)

An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex
por: Desai, Megha A., et al.
Publicado: (2015)

Proteins pinpoint double strand breaks
por: Cox, Michael M
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_cbmb4s287vc7v9e56rlttimeft