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Astragalin Suppresses Inflammatory Responses and Bone Destruction in Mice With Collagen-Induced Arthritis and in Human Fibroblast-Like Synoviocytes
Astragalin, as a bioactive flavonoid with anti-inflammatory, antioxidant, and protective properties, provides a potential agent for rheumatoid arthritis (RA). In this study, its therapeutic efficacy and the underlying mechanisms were explored using DBA/1J mice with collagen-induced arthritis (CIA)....
Autores principales: | Jia, Qingyun, Wang, Tengteng, Wang, Xiaoyun, Xu, Hao, Liu, Yang, Wang, Yongjun, Shi, Qi, Liang, Qianqian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379316/ https://www.ncbi.nlm.nih.gov/pubmed/30809149 http://dx.doi.org/10.3389/fphar.2019.00094 |
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