P2Y12 regulates microglia activation and excitatory synaptic transmission in spinal lamina II neurons during neuropathic pain in rodents

Peripheral nerve injury causes neuropathic pain and microglia activation. P2Y12 receptors on microglia are thought to be a key player in the surveillance of the local environment, but whether or how these receptors are engaged in the cross-talk between microglia and neurons of the dorsal horn remain...

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Detalles Bibliográficos
Autores principales: Yu, Tingting, Zhang, Xin, Shi, Haosong, Tian, Jinge, Sun, Lingling, Hu, Xueming, Cui, Wenqiang, Du, Dongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379416/
https://www.ncbi.nlm.nih.gov/pubmed/30778044
http://dx.doi.org/10.1038/s41419-019-1425-4

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