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Flagellar cAMP signaling controls trypanosome progression through host tissues

The unicellular parasite Trypanosoma brucei is transmitted between mammals by tsetse flies. Following the discovery that flagellar phosphodiesterase PDEB1 is required for trypanosomes to move in response to signals in vitro (social motility), we investigated its role in tsetse flies. Here we show th...

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Detalles Bibliográficos
Autores principales: Shaw, Sebastian, DeMarco, Stephanie F., Rehmann, Ruth, Wenzler, Tanja, Florini, Francesca, Roditi, Isabel, Hill, Kent L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379439/
https://www.ncbi.nlm.nih.gov/pubmed/30778051
http://dx.doi.org/10.1038/s41467-019-08696-y

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