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Association of PXR and CAR Polymorphisms and Antituberculosis Drug-Induced Hepatotoxicity

A combination therapy of multiple drugs including isoniazid, rifampicin, ethambutol and pyrazinamide has been proven to be an effective option for the vast majority of tuberculosis (TB) patients. However, various adverse drug reactions (ADRs) limit its merit, with anti-TB drug-induced hepatotoxicity...

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Detalles Bibliográficos
Autores principales:	Wang, Yu, Xiang, Xi, Huang, Wei-Wei, Sandford, Andrew J, Wu, Shou-Quan, Zhang, Miao-Miao, Wang, Ming-Gui, Chen, Guo, He, Jian-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379441/ https://www.ncbi.nlm.nih.gov/pubmed/30778091 http://dx.doi.org/10.1038/s41598-018-38452-z

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