The Role of IL-10 in Malaria: A Double Edged Sword

IL-10 produced by CD4(+) T cells suppresses inflammation by inhibiting T cell functions and the upstream activities of antigen presenting cells (APCs). IL-10 was first identified in Th2 cells, but has since been described in IFNγ-producing Tbet(+) Th1, FoxP3(+) CD4(+) regulatory T (Treg) and IL-17-p...

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Detalles Bibliográficos
Autores principales: Kumar, Rajiv, Ng, Susanna, Engwerda, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379449/
https://www.ncbi.nlm.nih.gov/pubmed/30809232
http://dx.doi.org/10.3389/fimmu.2019.00229

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