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Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8(+) Dendritic Cells

Apoptotic cell death of Dendritic cells (DCs) is critical for immune homeostasis. Although intrinsic mechanisms controlling DC death have not been fully characterized up to now, experimentally enforced inhibition of DC-death causes various autoimmune diseases in model systems. We have generated mice...

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Detalles Bibliográficos
Autores principales: Zwick, Markus, Ulas, Thomas, Cho, Yi-Li, Ried, Christine, Grosse, Leonie, Simon, Charlotte, Bernhard, Caroline, Busch, Dirk H., Schultze, Joachim L., Buchholz, Veit R., Stutte, Susanne, Brocker, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379467/
https://www.ncbi.nlm.nih.gov/pubmed/30809231
http://dx.doi.org/10.3389/fimmu.2019.00222