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Serological response to influenza vaccination among adults hospitalized with community‐acquired pneumonia
Ninety‐five adults enrolled in the Etiology of Pneumonia in the Community study with negative admission influenza polymerase chain reaction (PCR) tests received influenza vaccination during hospitalization. Acute and convalescent influenza serology was performed. After vaccination, seropositive (≥1:...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379631/ https://www.ncbi.nlm.nih.gov/pubmed/30485702 http://dx.doi.org/10.1111/irv.12622 |
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author | Pratt, Caroline Quinn Zhu, Yuwei Grijalva, Carlos G. Wunderink, Richard G. Mark Courtney, D. Waterer, Grant Levine, Min Z Jefferson, Stacie Self, Wesley H. Williams, Derek J. Finelli, Lynn Bramley, Anna M. Edwards, Kathryn M. Jain, Seema Anderson, Evan J. |
author_facet | Pratt, Caroline Quinn Zhu, Yuwei Grijalva, Carlos G. Wunderink, Richard G. Mark Courtney, D. Waterer, Grant Levine, Min Z Jefferson, Stacie Self, Wesley H. Williams, Derek J. Finelli, Lynn Bramley, Anna M. Edwards, Kathryn M. Jain, Seema Anderson, Evan J. |
author_sort | Pratt, Caroline Quinn |
collection | PubMed |
description | Ninety‐five adults enrolled in the Etiology of Pneumonia in the Community study with negative admission influenza polymerase chain reaction (PCR) tests received influenza vaccination during hospitalization. Acute and convalescent influenza serology was performed. After vaccination, seropositive (≥1:40) hemagglutination antibody titers (HAI) were achieved in 55% to influenza A(H1N1)pdm09, 58% to influenza A(H3N2), 77% to influenza B (Victoria), and 74% to influenza B (Yamagata) viruses. Sixty‐six (69%) patients seroconverted (≥4‐fold HAI rise) to ≥1 strain. Failure to seroconvert was associated with diabetes, bacterial detection, baseline seropositive titers for influenza B (Yamagata), and influenza vaccination in the previous season. |
format | Online Article Text |
id | pubmed-6379631 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-63796312019-03-01 Serological response to influenza vaccination among adults hospitalized with community‐acquired pneumonia Pratt, Caroline Quinn Zhu, Yuwei Grijalva, Carlos G. Wunderink, Richard G. Mark Courtney, D. Waterer, Grant Levine, Min Z Jefferson, Stacie Self, Wesley H. Williams, Derek J. Finelli, Lynn Bramley, Anna M. Edwards, Kathryn M. Jain, Seema Anderson, Evan J. Influenza Other Respir Viruses Short Article Ninety‐five adults enrolled in the Etiology of Pneumonia in the Community study with negative admission influenza polymerase chain reaction (PCR) tests received influenza vaccination during hospitalization. Acute and convalescent influenza serology was performed. After vaccination, seropositive (≥1:40) hemagglutination antibody titers (HAI) were achieved in 55% to influenza A(H1N1)pdm09, 58% to influenza A(H3N2), 77% to influenza B (Victoria), and 74% to influenza B (Yamagata) viruses. Sixty‐six (69%) patients seroconverted (≥4‐fold HAI rise) to ≥1 strain. Failure to seroconvert was associated with diabetes, bacterial detection, baseline seropositive titers for influenza B (Yamagata), and influenza vaccination in the previous season. John Wiley and Sons Inc. 2018-12-17 2019-03 /pmc/articles/PMC6379631/ /pubmed/30485702 http://dx.doi.org/10.1111/irv.12622 Text en © 2018 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Article Pratt, Caroline Quinn Zhu, Yuwei Grijalva, Carlos G. Wunderink, Richard G. Mark Courtney, D. Waterer, Grant Levine, Min Z Jefferson, Stacie Self, Wesley H. Williams, Derek J. Finelli, Lynn Bramley, Anna M. Edwards, Kathryn M. Jain, Seema Anderson, Evan J. Serological response to influenza vaccination among adults hospitalized with community‐acquired pneumonia |
title | Serological response to influenza vaccination among adults hospitalized with community‐acquired pneumonia |
title_full | Serological response to influenza vaccination among adults hospitalized with community‐acquired pneumonia |
title_fullStr | Serological response to influenza vaccination among adults hospitalized with community‐acquired pneumonia |
title_full_unstemmed | Serological response to influenza vaccination among adults hospitalized with community‐acquired pneumonia |
title_short | Serological response to influenza vaccination among adults hospitalized with community‐acquired pneumonia |
title_sort | serological response to influenza vaccination among adults hospitalized with community‐acquired pneumonia |
topic | Short Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379631/ https://www.ncbi.nlm.nih.gov/pubmed/30485702 http://dx.doi.org/10.1111/irv.12622 |
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